Ergothioneine biosynthesis protein egtb
Webergothioneine biosynthesis protein EgtB. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. egtB ergothioneine biosynthesis protein EgtB [] Gene ID: 15149496, updated on 23-Sep-2024 ... WebegtB. Status. UniProtKB reviewed (Swiss-Prot) ... (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. Ergothioneine is an antioxidant that protects mycobacteria from oxidative stress. ... Protein-protein interaction databases. STRING. 83332 ...
Ergothioneine biosynthesis protein egtb
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WebJan 1, 2024 · As EgtBs from Methylobacterium bacteria are reported to use l-cysteine as a sulfur donor in ergothioneine biosynthesis, egtB from Methylobacterium was expressed with M. smegmatis egtDE in the l-cysteine ... and SDS-PAGE of the purified enzyme showed a major protein band at 45 kDa. Biosynthesis of LS was performed using the purified β ... Webergothioneine biosynthesis protein EgtC: ergothioneine biosynthesis I (bacteria) TBHG_RS19425: 1.14.99.50: 0.999: ergothioneine biosynthesis protein EgtB: ergothioneine biosynthesis I (bacteria) embC: none: 0.992: arabinosyltransferase EmbC: mycolyl-arabinogalactan-peptidoglycan complex biosynthesis:
WebMar 7, 2024 · Primary Citation of Related Structures: 6O6L, 6O6M. PubMed Abstract: Ergothioneine is a thiohistidine derivative with potential benefits on many aging-related diseases. The central step of aerobic ergothioneine biosynthesis is the oxidative C-S bond formation reaction catalyzed by mononuclear nonheme iron sulfoxide synthases … WebNov 27, 2024 · To date, only two enzymes are known to carry out this function: the sulfoxide synthase EgtB, involved in the biosynthesis of ergothioneine in fungi and bacteria, and the 5-histidylcysteine sulfoxide synthase OvoA, involved in the biosynthesis of ovothiols, found in the eggs and biological fluids of marine invertebrates, some proteobacteria and ...
WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … WebBackground: Anthracyclines such as doxorubicin remain a primary treatment for hematological malignancies and breast cancers. However, cardiotoxicity induced by anthracyclines, possibly leading to heart failure, severely limits their application. The pathological mechanisms of anthracycline-induced cardiac injury are believed to involve …
WebOverview. Ergothioneine is an amino acid that is found mainly in mushrooms, as well as red and black beans. It is also found in animals that have eaten grasses containing …
WebNov 16, 2011 · Ergothioneine biosynthesis protein EgtB automatic annotation. Gene names. Ordered locus names. Cabther_A1318 Imported. Organism names. Organism. Chloracidobacterium thermophilum (strain B) Imported. Taxonomic identifier. 981222 NCBI. Taxonomic lineage. Bacteria > Acidobacteria > Blastocatellia > Chloracidobacterium. … granville hollywoodWebRecent studies have reported the characterization of ovoA gene sequence and OvoA protein primary structure in several species of marine invertebrates [9,15]. Similar to ergothioneine synthase (EgtB), the other known sulfoxide synthase that contributes to the biosynthesis of the biothiol compound ergothioneine, OvoA shows a conserved N … granville house telford and wrekin councilWebDec 10, 2014 · The non-heme iron enzyme EgtB catalyzes O2 -dependent C-S bond formation between γ-glutamyl cysteine and N-α-trimethyl histidine as the central step in ergothioneine biosynthesis. Both, the catalytic … chipperfield villageWebFeb 28, 2024 · The central step of aerobic ergothioneine biosynthesis is the oxidative C-S bond formation reaction catalyzed by mononuclear … granville house 2 tettenhall road wv1 4sbWebDec 1, 2024 · EgtD belongs to the MT_33 methyltransferase superfamily and is the only enzyme that occurs in all known ergothioneine biosynthetic pathways ( Figure 1). Most … granville housing authorityWebAug 18, 2024 · Ergothioneine (EGT) has a unique antioxidant ability and diverse beneficial effects on human health. But the content of EGT is very low in its natural producing … chipperfield united kingdomWebJan 1, 2024 · Metabolic pathways for ergothioneine synthesis. Metabolic pathways for ergothioneine biosynthesis in M. smegmatis (EgtA, EgtB, EgtC, EgtD, and EgtE) and … granville il weather radar